Versatile Polydopamine Platforms: Synthesis and Promising Applications for Surface Modification and Advanced Nanomedicine.,ACS Nano

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Versatile Polydopamine Platforms: Synthesis and Promising Applications for Surface Modification and Advanced Nanomedicine.
ACS Nano ( IF 15.8 ) Pub Date : 2019-08-01 00:00:00 , DOI: 10.1021/acsnano.9b04436
Wei Cheng ₁ , Xiaowei Zeng _{1,

2} , Hongzhong Chen ₂ , Zimu Li ₁ , Wenfeng Zeng ₁ , Lin Mei ₁ , Yanli Zhao _{2,

3}

Affiliation

As a mussel-inspired material, polydopamine (PDA), possesses many properties, such as a simple preparation process, good biocompatibility, strong adhesive property, easy functionalization, outstanding photothermal conversion efficiency, and strong quenching effect. PDA has attracted increasingly considerable attention because it provides a simple and versatile approach to functionalize material surfaces for obtaining a variety of multifunctional nanomaterials. In this review, recent significant research developments of PDA including its synthesis and polymerization mechanism, physicochemical properties, different nano/microstructures, and diverse applications are summarized and discussed. For the sections of its applications in surface modification and biomedicine, we mainly highlight the achievements in the past few years (2016–2019). The remaining challenges and future perspectives of PDA-based nanoplatforms are discussed rationally at the end. This timely and overall review should be desirable for a wide range of scientists and facilitate further development of surface coating methods and the production of PDA-based materials.

中文翻译：

多功能的聚多巴胺平台：表面改性和先进的纳米医学的合成和有希望的应用。

聚多巴胺（PDA）作为贻贝类材料，具有制备过程简单，生物相容性好，粘合性能强，易于官能化，光热转化效率高，猝灭效果强等多种特性。PDA吸引了越来越多的关注，因为它提供了一种简单而通用的方法来功能化材料表面以获得各种多功能纳米材料。在这篇综述中，对PDA的近期重要研究进展进行了总结和讨论，包括其合成和聚合机理，理化性质，不同的纳米/微结构以及各种应用。对于其在表面修饰和生物医学中的应用部分，我们主要强调过去几年（2016-2019年）取得的成就。最后，合理地讨论了基于PDA的纳米平台的其余挑战和未来前景。这种及时和全面的审查对于广泛的科学家来说应该是理想的，并有助于表面涂层方法的进一步发展和基于PDA的材料的生产。

更新日期：2019-08-01

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