Bioprinting: A Tumor‐on‐a‐Chip System with Bioprinted Blood and Lymphatic Vessel Pair (Adv. Funct. Mater. 31/2019),Advanced Functional Materials

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Bioprinting: A Tumor‐on‐a‐Chip System with Bioprinted Blood and Lymphatic Vessel Pair (Adv. Funct. Mater. 31/2019)
Advanced Functional Materials ( IF 18.5 ) Pub Date : 2019-07-29 , DOI: 10.1002/adfm.201970217
Xia Cao _{1,

2} , Ramla Ashfaq _{2,

3} , Feng Cheng ₂ , Sushila Maharjan ₂ , Jun Li ₂ , Guoliang Ying ₂ , Shabir Hassan ₂ , Haiyan Xiao _{4,

5} , Kan Yue _{4,

5} , Yu Shrike Zhang ₂

Affiliation

In article number 1807173, Yu Shrike Zhang and co‐workers report the development of an improved tumor‐on‐a‐chip model consisting of a bioprinted hollow, perfusable blood vessel for liquid delivery and a hollow, single end‐blinded lymphatic vessel for interstitial fluid draining, hosted in a 3D tumor microenvironment‐like hydrogel matrix. This model featuring the biomimetic local microcirculation exhibits well‐controlled transport of biomolecules and anti‐cancer drugs.

中文翻译：

生物打印：带有生物打印的血液和淋巴管对的芯片肿瘤系统（Adv。Funct。Mater。31/2019）

在文章1807173中，Yu Shrike Zhang及其同事报告了一种改进的芯片上肿瘤模型的开发，该模型包括生物打印的空心可灌注血管（用于液体输送）和空心单端盲淋巴管（用于组织间质）在3D肿瘤微环境状水凝胶基质中进行液体引流。该模型具有仿生局部微循环特性，可很好地控制生物分子和抗癌药物的运输。

更新日期：2019-07-29

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