TMSCl-Catalyzed Electrophilic Thiocyano Oxyfunctionalization of Alkenes Using N-Thiocyano-dibenzenesulfonimide,Organic Letters

当前位置： X-MOL 学术 › Org. Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

TMSCl-Catalyzed Electrophilic Thiocyano Oxyfunctionalization of Alkenes Using N-Thiocyano-dibenzenesulfonimide
Organic Letters ( IF 4.9 ) Pub Date : 2019-06-20 00:00:00 , DOI: 10.1021/acs.orglett.9b01706
Ai-Hui Ye ₁ , Ye Zhang ₁ , Yu-Yang Xie ₁ , Hui-Yun Luo ₁ , Jia-Wei Dong ₁ , Xiao-Dong Liu ₁ , Xu-Feng Song ₁ , Tongmei Ding ₁ , Zhi-Min Chen ₁

Affiliation

Numerous electrophilic thiocyano oxyfunctionalization reactions of alkenes have been achieved using N-thiocyano-dibenzenesulfonimide, which is a new electrophilic thiocyanation reagent and could be easily prepared in two steps from dibenzenesulfonimide. This approach provides efficient, simple, and modular methods for the formation of SCN-containing heterocycles such as lactones, tetrahydrofurans, dihydrofurans, and dihydrobenzofurans in moderate to excellent yields. Meanwhile, diverse oxa-quaternary centers were rapidly constructed. Additionally, this protocol is free of transition metals and features broad substrate toleraance and mild reaction conditions.

中文翻译：

N-硫代氰基-二苯磺酰亚胺对TMSC1催化的烯烃亲电硫代氰基氧基官能化

使用N-硫氰基-二苯磺酰亚胺是一种新型的亲电子硫氰化试剂，可以很容易地从二苯磺酰亚胺分两步制备，实现了烯烃的许多亲电子硫氰基氧基官能化反应。该方法提供了有效，简单和模块化的方法，以中等到极好的收率形成含SCN的杂环，如内酯，四氢呋喃，二氢呋喃和二氢苯并呋喃。同时，迅速建立了各种各样的氧杂-季铵盐中心。此外，该方案不含过渡金属，并具有宽广的底物耐受性和温和的反应条件。

更新日期：2019-06-20

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南