Emeriones A–C (1–3), three highly methylated polyketides with bicyclo[4.2.0]octene and 3,6-dioxabicyclo[3.1.0]hexane functionalities, were isolated from Emericella nidulans. An additional peroxide bridge in compound 3 led to the construction of an unexpected 7,8-dioxatricyclo[4.2.2.0^2,5]decene scaffold. The structures of 1–3 were elucidated by comprehensive spectroscopic techniques, and their absolute configurations were confirmed by single-crystal X-ray crystallographic analyses and ECD calculations. Compound 1 shows weak inhibitory effects on NO production in LPS-induced RAW264.7 cells.

中文翻译：

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Emeriones AC：三种高甲基化的聚酮化合物，具有双环[4.2.0]辛烯和3,6-二氧杂双环[3.1.0]己烷官能团的杜鹃花。

Emeriones A-C（1 - 3），三个与二环[4.2.0]辛烯和3,6-二氧杂双环高度甲基化聚酮化合物[3.1.0]己烷的功能，是从分离裸胞壳构巢曲霉。化合物3中的另一个过氧化物桥导致意外的7,8-二氧杂三环[4.2.2.0 ^2,5 ]癸烯骨架的构建。的结构1 - 3通过综合光谱技术阐明，和它们的绝对构型通过单晶X射线晶体分析和ECD的计算证实。在LPS诱导的RAW264.7细胞中，化合物1对NO产生弱的抑制作用。