This paper describes the development of a new variant of stereoselective strain-release driven reactions (formal homo [3 + 2] dipolar cycloadditions) which utilize housane (1) to construct functionalized amino alcohols and pyridine-substituted cyclopentanes in two to three steps from simple and easily available building blocks (nitrones and pyridine N-oxides respectively).

中文翻译：

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应变释放驱动的环加成反应，用于功能化吡啶和氨基醇的快速构建

本文介绍了立体选择性应变释放驱动反应的新变体（正式的同型[3 + 2]偶极环加成反应）的开发过程，该反应利用husane（1）从简单的两步到三步即可构建官能化的氨基醇和吡啶取代的环戊烷和容易获得的构件（分别是硝酮和吡啶N-氧化物）。