There is an unmet clinical need for a low cost and easy to use wearable devices for continuous cardiovascular health monitoring. A flexible and wearable wristband, based on microelectromechanical sensor (MEMS) elements array was developed to support this need. The performance of the device in cardiovascular monitoring was investigated by (i) comparing the arterial pressure waveform recordings to the gold standard, invasive catheter recording (n = 18), (ii) analyzing the ability to detect irregularities of the rhythm (n = 7), and (iii) measuring the heartrate monitoring accuracy (n = 31). Arterial waveforms carry important physiological information and the comparison study revealed that the recordings made with the wearable device and with the gold standard device resulted in almost identical (r = 0.9–0.99) pulse waveforms. The device can measure the heart rhythm and possible irregularities in it. A clustering analysis demonstrates a perfect classification accuracy between atrial fibrillation (AF) and sinus rhythm. The heartrate monitoring study showed near perfect beat-to-beat accuracy (sensitivity = 99.1%, precision = 100%) on healthy subjects. In contrast, beat-to-beat detection from coronary artery disease patients was challenging, but the averaged heartrate was extracted successfully (95% CI: −1.2 to 1.1 bpm). In conclusion, the results indicate that the device could be useful in remote monitoring of cardiovascular diseases and personalized medicine.

对于低成本和易于使用的可穿戴设备进行连续心血管健康监测的临床需求尚未得到满足。为了满足这一需求，开发了一种基于微机电传感器（MEMS）元件阵列的柔性可穿戴腕带。通过（i）将动脉压波形记录与黄金标准比较，有创导管记录（n  = 18），（ii）分析发现节律不规则的能力（n  = 7 ），研究了该设备在心血管监测中的性能。），以及（iii）测量心率监测准确性（n = 31）。动脉波形携带重要生理信息和比较研究表明，与可穿戴设备，并与金标准设备所做的记录导致几乎相同（ř = 0.9–0.99）脉冲波形。该设备可以测量心律和心律不齐。聚类分析表明房颤（AF）和窦性心律之间的分类准确度很高。心率监测研究显示，健康受试者的心跳精确度接近完美（灵敏度= 99.1％，精确度= 100％）。相反，从冠心病患者的逐搏检测具有挑战性，但平均心率已成功提取（95％CI：-1.2至1.1 bpm）。总之，结果表明该设备可用于心血管疾病和个性化医学的远程监测。