A Novel Amphiphilic AIE Molecule and Its Application in Thermosensitive Liposome,ChemistrySelect

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A Novel Amphiphilic AIE Molecule and Its Application in Thermosensitive Liposome
ChemistrySelect ( IF 1.9 ) Pub Date : 2019-05-07 , DOI: 10.1002/slct.201900976
Yun‐Hui Zhao _{1,

2} , Yueyang Luo ₁ , Tao Guo ₃ , Zilong Tang ₁ , Zhihua Zhou ₁

Affiliation

A novel amphiphilic aggregation induced emission (AIE) molecule was prepared from tetraphenyl ethylene unit modified with long chain and carboxylic acid. It acted as an effective ingredient to form liposomes through self‐assembly with phospholipids. The smart nanomaterial exhibited good aggregation‐induced emission (AIE) characteristic and excellent response to temperature below 50 °C. Moreover, in vitro imaging shows that it has the potential to be used in biomedical field as drug delivery system.

中文翻译：

新型两亲性AIE分子及其在热敏脂质体中的应用

由长链和羧酸修饰的四苯基乙烯单元制备了一种新型的两亲性聚集诱导发射（AIE）分子。它是通过与磷脂自组装形成脂质体的有效成分。智能纳米材料表现出良好的聚集诱导发射（AIE）特性，并且对低于50°C的温度具有出色的响应。此外，体外成像显示它具有作为药物递送系统在生物医学领域中使用的潜力。

更新日期：2019-05-07

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