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Retrosplenial cortex and its role in cue-specific learning and memory.
Neuroscience & Biobehavioral Reviews ( IF 7.5 ) Pub Date : 2019-05-02 , DOI: 10.1016/j.neubiorev.2019.04.016 Travis P Todd 1 , Danielle I Fournier 1 , David J Bucci 1
Neuroscience & Biobehavioral Reviews ( IF 7.5 ) Pub Date : 2019-05-02 , DOI: 10.1016/j.neubiorev.2019.04.016 Travis P Todd 1 , Danielle I Fournier 1 , David J Bucci 1
Affiliation
The retrosplenial cortex (RSC) contributes to spatial navigation, as well as contextual learning and memory. However, a growing body of research suggests that the RSC also contributes to learning and memory for discrete cues, such as auditory or visual stimuli. In this review, we summarize and assess the Pavlovian and instrumental conditioning experiments that have examined the role of the RSC in cue-specific learning and memory. We use the term cue-specific to refer to these putatively non-spatial conditioning paradigms that involve discrete cues. Although these paradigms emphasize behavior related to cue presentations, we note that cue-specific learning and memory always takes place against a background of contextual stimuli. We review multiple ways by which contexts can influence responding to discrete cues and suggest that RSC contributions to cue-specific learning and memory are intimately tied to contextual learning and memory. Indeed, although the RSC is involved in several forms of cue-specific learning and memory, we suggest that many of these can be linked to processing of contextual stimuli.
中文翻译:
脾后皮质及其在特定于提示的学习和记忆中的作用。
脾后皮质(RSC)有助于空间导航以及上下文学习和记忆。但是,越来越多的研究表明,RSC还有助于听觉或视觉刺激等离散线索的学习和记忆。在这篇综述中,我们总结并评估了帕夫洛夫式和器乐性条件实验,这些实验检查了RSC在特定于提示的学习和记忆中的作用。我们使用术语“特定于线索”来指代这些涉及离散线索的推定非空间条件范式。尽管这些范例强调了与提示表达有关的行为,但我们注意到,特定于提示的学习和记忆始终是在上下文刺激的背景下进行的。我们回顾了上下文可以影响对离散线索的响应的多种方式,并提出RSC对特定于线索的学习和记忆的贡献与上下文学习和记忆密切相关。确实,尽管RSC涉及多种形式的特定于提示的学习和记忆,但我们建议其中许多可以与上下文刺激的处理相关联。
更新日期:2019-05-02
中文翻译:
脾后皮质及其在特定于提示的学习和记忆中的作用。
脾后皮质(RSC)有助于空间导航以及上下文学习和记忆。但是,越来越多的研究表明,RSC还有助于听觉或视觉刺激等离散线索的学习和记忆。在这篇综述中,我们总结并评估了帕夫洛夫式和器乐性条件实验,这些实验检查了RSC在特定于提示的学习和记忆中的作用。我们使用术语“特定于线索”来指代这些涉及离散线索的推定非空间条件范式。尽管这些范例强调了与提示表达有关的行为,但我们注意到,特定于提示的学习和记忆始终是在上下文刺激的背景下进行的。我们回顾了上下文可以影响对离散线索的响应的多种方式,并提出RSC对特定于线索的学习和记忆的贡献与上下文学习和记忆密切相关。确实,尽管RSC涉及多种形式的特定于提示的学习和记忆,但我们建议其中许多可以与上下文刺激的处理相关联。