AbstractThe authors describe an electrochemical dopamine sensor that is based on the use of electrochemically co-reduced graphene oxide (Er-GO) and gold nanoparticles (AuNPs) on an indium-tin oxide (ITO) electrode. The synergistic effects of Er-GO and Er-AuNPs promote electron transport in the modified ITO. This results in an excellent performance for voltammetric sensing of dopamine (DA). Under the optimum conditions and a typical working potential of −0.05 V (vs. Ag/AgCl), the ITO electrode has a linear response in the 0.02–200 μM DA concentration range and a low detection limit of 15 nM. The sensor also showed a good selectivity over ascorbic acid and uric acid. The feasibility of the method was studied by analyzing DA in cerebrospinal fluid of rats. Graphical abstractSchematic presentation of one-step electrochemical co-reduction of graphene oxide (GO) and gold nanoparticles (AuNPs) on an ITO electrode for voltammetric sensing of dopamine.

中文翻译：

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氧化铟锡电极上电化学还原氧化石墨烯和金纳米粒子，用于多巴胺的伏安传感

摘要作者描述了一种电化学多巴胺传感器，该传感器基于在氧化铟锡 (ITO) 电极上使用电化学共还原氧化石墨烯 (Er-GO) 和金纳米粒子 (AuNPs)。Er-GO 和 Er-AuNPs 的协同作用促进了改性 ITO 中的电子传输。这导致了多巴胺 (DA) 伏安法传感的优异性能。在最佳条件和 -0.05 V（相对于 Ag/AgCl）的典型工作电位下，ITO 电极在 0.02–200 μMD DA 浓度范围内具有线性响应，检测下限为 15 nM。该传感器还显示出对抗坏血酸和尿酸的良好选择性。通过分析大鼠脑脊液中的DA来研究该方法的可行性。