Vinyl Sulfoxonium Ylide: A New Vinyl Carbenoid Transfer Reagent for the Synthesis of Heterocycles,Synlett

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Vinyl Sulfoxonium Ylide: A New Vinyl Carbenoid Transfer Reagent for the Synthesis of Heterocycles
Synlett ( IF 1.7 ) Pub Date : 2019-04-10 , DOI: 10.1055/s-0037-1611771
Janakiram Vaitla _{1,

2} , Annette Bayer ₂ , Kathrin H. Hopmann _{1,

2}

Affiliation

Sulfoxonium ylides have recently gained prominence as safe carbenoid precursors in metal-catalyzed reactions. The stability and reactivity of sulfoxonium ylides depend on the substitution of the ylide carbon. The reactivity of vinyl-substituted sulfoxonium ylides is different and offers several advantages over known stabilized sulfoxonium ylides in the case of carbenoid transfer reactions. Herein, we provide an overview of early efforts in this area, with particular emphasis on our own recent development of sulfoxonium ylide-derived vinyl carbenoid transformations for N-Heterocycles. 1 Introduction 2 Classification of Sulfoxonium Ylides 3 Synthesis of Vinyl Sulfoxonium Ylides 4 [3+2] Annulation of Vinyl Sulfoxonium Ylides 5 [4+1] Annulation of Vinyl Sulfoxonium Ylides 6 Conclusion

中文翻译：

Vinyl Sulfoxonium Ylide：一种用于合成杂环的新型乙烯基类卡宾转移试剂

锍叶立德最近在金属催化反应中作为安全的类卡宾前体获得了突出地位。锍叶立德的稳定性和反应性取决于叶立德碳的取代。乙烯基取代的锍叶立德的反应性是不同的，并且在卡宾转移反应的情况下提供了优于已知稳定的锍叶立德的几个优点。在此，我们概述了该领域的早期工作，特别强调了我们自己最近开发的用于 N-杂环的 sulfoxonium ylide 衍生的乙烯基类卡宾转化。1 介绍 2 磺草酮叶立德的分类 3 乙烯基磺草醚叶立德的合成 4 [3+2] 乙烯基磺草醚叶立德的环化 5 [4+1] 乙烯基磺草酮叶立德的环化 6 结论

更新日期：2019-04-10

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