The separation of the ternary nonideal system ethyl acetate (EtAC)/ethanol (EtOH)/water with multiazeotropes is very important since they are always generated in the production process of n-butanol synthesis from ethanol, which is much more difficult due to the formation of the multiazeotrope and distillation boundary. Herein, a systematic conceptual design, optimization, and control approach for ternary extractive distillation of multiazeotrope mixtures EtAC/EtOH/water is proposed. The procedure involves entrainer screening, conceptual design, global optimization, process evaluation, and a robust control strategy. The optimization results demonstrate that the total annual cost, exergy loss, and carbon dioxide emissions of the proposed triple-column extractive distillation are significantly reduced compared with those of the existing process. Dynamic performances illustrate that the improved dual temperature and feedforward control strategy can well handle the three product purities, while two kinds of disturbances (i.e., feed flow rate and composition) are introduced.

中文翻译：

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多共沸物分离乙酸乙酯/乙醇/水的三塔萃取精馏的优化设计和有效控制

具有多共沸物的三元非理想体系乙酸乙酯（EtAC）/乙醇（EtOH）/水的分离非常重要，因为它们总是在n的生产过程中产生由乙醇合成丁醇，由于多共沸物和蒸馏边界的形成，因此困难得多。在此，提出了多共沸混合物EtAC / EtOH /水的三元萃取蒸馏的系统概念设计，优化和控制方法。该过程涉及夹带剂筛选，概念设计，全局优化，过程评估和可靠的控制策略。优化结果表明，与现有工艺相比，拟议的三塔萃取精馏的总年度成本，火用损失和二氧化碳排放量显着降低。动态性能表明，改进的双重温度和前馈控制策略可以很好地处理三种产品纯度，而两种干扰（即