Graphene oxide (GO) modified with ferrocene (Fc) was successfully assembled via the π-π interaction (GO-Fc) and had the features of large surface area and high loading. Then, a novel composite was synthesized via β-cyclodextrin (β-CD) functionalized GO-Fc by combining the advantages of GO-Fc and β-CD. An efficient chiral electrochemical sensing interface was constructed by using the rGO-Fc-CD composite as the electrode modification for the recognition of phenylalanine (Phe) enantiomers. The successful synthesis of the composites was confirmed by FTIR, XRD, TGA, SEM, and XPS results. The host-guest inclusion interaction was detected by ultraviolet spectroscopy and DPV. The recognition results demonstrated that the rGO-Fc-CD/GCE showed a higher chiral recognition capability for L-Phe than for D-Phe. The enantioselectivity coefficient (I_D/I_L) of the proposed sensor was 2.47. The LOD values of 27 nM and 52 nM (S/N = 3) for L-Phenylalanine and D-Phenylalanine were obtained for this electrochemical sensor. The as-synthesized material was successfully exploited for the recognition of Phe enantiomers, indicating that the developed sensor has wide application prospects.

二茂铁（Fc）修饰的氧化石墨烯（GO）通过π-π相互作用（GO-Fc）成功组装，具有表面积大，负载高的特点。然后，结合GO-Fc和β-CD的优点，通过β-环糊精（β-CD）功能化的GO-Fc合成了新型复合材料。通过使用rGO-Fc-CD复合材料作为识别苯丙氨酸（Phe）对映异构体的电极修饰物，构建了有效的手性电化学传感界面。FTIR，XRD，TGA，SEM和XPS结果证实了复合材料的成功合成。通过紫外光谱和DPV检测宿主-客体的夹杂物相互作用。识别结果表明，rGO-Fc-CD / GCE对L-Phe的手性识别能力高于对D-Phe的手性。对映选择性系数（I提出的传感器的_D / I _L）为2.47。对于该电化学传感器，L-苯丙氨酸和D-苯丙氨酸的LOD值为27 nM和52 nM（S / N = 3）。合成后的材料已成功用于Phe对映体的识别，这表明开发的传感器具有广阔的应用前景。