Davidson’s plum is a native Australian fruit used traditionally as food and medicine. The fruit contains anthocyanins as glucosides and sambubiosides of cyanidin and peonidin (691 mg/100 g of dried pulp) with rutin and quercetin glycosides (193 mg/100 g). Dietary supplementation of Davidson’s plum at approximately 8 mg anthocyanins/kg/day in rats attenuated the signs of metabolic syndrome induced by high-carbohydrate, high-fat diet. Davidson’s plum reduced visceral fat accumulation, total abdominal fat weight, size of retroperitoneal adipocytes, and plasma triglycerides and non-esterified fatty acids, normalised blood pressure, reduced left ventricular stiffness, decreased infiltration of inflammatory cells in both left ventricle and liver, decreased collagen deposition in heart, and reduced both fat vacuoles in liver and obesity-induced degeneration of knee cartilage. There were no changes in glucose tolerance with treatment. Davidson’s plum reduced colonic Clostridiaceae spp, and increased Turicibacter spp. and Akkermansia muciniphila. Our findings indicate that Davidson’s plum is a potential complementary treatment for metabolic syndrome.

戴维森的李子是一种澳大利亚本土水果，传统上被用作食品和药品。水果中含有花青素作为苷和花青素和peonidin（691毫克/ 100克干果肉）的桑布比苷，以及芦丁和槲皮素糖苷（193毫克/ 100克）。在大鼠中以大约8毫克的花青素/千克/天的量补充戴维森李子，可减轻高碳水化合物，高脂饮食诱导的代谢综合症的症状。Davidson的李子减少了内脏脂肪的积累，腹部总脂肪的重量，腹膜后脂肪细胞的大小，血浆甘油三酸酯和非酯化脂肪酸的含量，血压正常化，左心室僵硬度降低，左心室和肝脏中炎性细胞的浸润减少，胶原蛋白减少沉积在心脏中 并减少了肝脏中的脂肪液泡和肥胖引起的膝关节软骨变性。治疗后葡萄糖耐量没有变化。戴维森的李子减少了结肠梭菌属和轮状杆菌属增加。和Akkermansia muciniphila。我们的发现表明，戴维森李子是代谢综合征的潜在补充疗法。