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Drug Delivery: Modular Metal–Organic Polyhedra Superassembly: From Molecular‐Level Design to Targeted Drug Delivery (Adv. Mater. 12/2019)
Advanced Materials ( IF 27.4 ) Pub Date : 2019-03-19 , DOI: 10.1002/adma.201970082 Wei Zhu 1 , Jimin Guo 1 , Yi Ju 2 , Rita E. Serda 3 , Jonas G. Croissant 1 , Jin Shang 4 , Eric Coker 5 , Jacob Ongudi Agola 1 , Qi‐Zhi Zhong 2 , Yuan Ping 6 , Frank Caruso 2 , C. Jeffrey Brinker 1
Advanced Materials ( IF 27.4 ) Pub Date : 2019-03-19 , DOI: 10.1002/adma.201970082 Wei Zhu 1 , Jimin Guo 1 , Yi Ju 2 , Rita E. Serda 3 , Jonas G. Croissant 1 , Jin Shang 4 , Eric Coker 5 , Jacob Ongudi Agola 1 , Qi‐Zhi Zhong 2 , Yuan Ping 6 , Frank Caruso 2 , C. Jeffrey Brinker 1
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A novel and modular super‐assembly approach combines the synergistic advantages of metal–organic cage super‐assemblies (e.g., highly controlled architecture, high payloads of multiple cargos) and micelles (e.g., low inherent toxicity) for targeted drug delivery is presented by Wei Zhu, C. Jeffrey Brinker, and co‐workers in article number 1806774. By modification of the targeting moieties, targeted drug delivery to cancer cells is realized.
中文翻译：
药物输送：模块化金属-有机多面体超级组装：从分子水平设计到靶向药物输送（Adv。Mater。12/2019）
Wei提出了一种新颖的，模块化的超级组装方法，该方法结合了金属-有机笼式超级组装（例如，高度可控的体系结构，多种货物的有效载荷）和胶束（例如，低内在毒性）的协同优势，从而可以有针对性地进行药物输送Zhu，C。Jeffrey Brinker和同事在文章编号1806774中。通过修饰靶向部分，实现了向癌细胞的靶向药物递送。
更新日期：2019-03-19
中文翻译：
药物输送：模块化金属-有机多面体超级组装：从分子水平设计到靶向药物输送（Adv。Mater。12/2019）
Wei提出了一种新颖的，模块化的超级组装方法，该方法结合了金属-有机笼式超级组装（例如，高度可控的体系结构，多种货物的有效载荷）和胶束（例如，低内在毒性）的协同优势，从而可以有针对性地进行药物输送Zhu，C。Jeffrey Brinker和同事在文章编号1806774中。通过修饰靶向部分，实现了向癌细胞的靶向药物递送。
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