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Organocatalytic Asymmetric Synthesis of Bridged O,O‐Ketals with Spirooxindole Motif
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2019-04-01 , DOI: 10.1002/ejoc.201900120
Megha Balha 1 , Chintan Soni 2 , Subhas Chandra Pan 1
Affiliation  

The first organocatalytic enantioselective synthesis of bridged O,O‐ketals with spirooxindole motif has been developed. The spirooxindole products were isolated in good to high yields with high diastereo‐ and enantioselectivities under mild and operationally simple reaction conditions.
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中文翻译:

螺氧杂吲哚基团的有机催化不对称合成桥联O,O-酮

已开发出具有螺吲哚图案的桥连的OO-缩酮的第一个有机催化对映选择性合成。在温和且操作简单的反应条件下,以较高的非对映异构体和对映体选择性高至高收率分离出了吡咯并吲哚产物。
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更新日期:2019-04-01
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