Eleven previously undescribed compounds including two triterpenes, ilexchinenin A and ilexchinenin B, and nine triterpenoid saponins, ilexchinenosides A-I, along with twelve known triterpenoids were isolated from the leaves of Ilex chinensis Sims (Aquifoliaceae). Their structures were elucidated by spectroscopic analysis and comparison with known compounds. Furthermore, eight compounds exhibited significant inhibitory effects on NO production of lipopolysaccharide (LPS)-induced murine macrophages, while nine compounds exhibited potent hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in in vitro assays.

中文翻译：

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冬青叶中的三萜类化合物

从冬青 (Aquifoliaceae) 的叶子中分离出 11 种以前未描述的化合物，包括两种三萜、ilexchinenin A 和 ilexchinenin B，以及 9 种三萜皂苷、ilexchinenosides AI，以及 12 种已知的三萜。它们的结构通过光谱分析和与已知化合物的比较来阐明。此外，8 种化合物对脂多糖 (LPS) 诱导的小鼠巨噬细胞的 NO 产生具有显着的抑制作用，而 9 种化合物在体外试验中对 N-乙酰-对氨基苯酚 (APAP) 诱导的 HepG2 细胞损伤表现出有效的保肝活性。