In article number 1801363 Shiladitya Sengupta, Ali Khademhosseini and co‐workers show organ‐on‐a‐chip systems can provide high‐throughput platforms for drug development, which could potentially bridge the gap between 2D cell culture and animal models. With recent breakthroughs in anticancer immunotherapies, there is an increasing interest in organotypic models for anti‐cancer immunotherapy development. This study reviews current progress in cancer‐on‐a‐chip and immune organ‐on‐a‐chip systems with an emphasis on their potential for drug development.

中文翻译：

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芯片上器官：用于癌症和免疫器官建模的芯片上器官（Adv。Healthcare Mater。4/2019）

在编号1801363 Shiladitya Sengupta，Ali Khademhosseini及其同事的文章中显示，片上器官系统可以为药物开发提供高通量平台，这有可能弥合2D细胞培养与动物模型之间的鸿沟。随着抗癌免疫疗法的最新突破，对用于抗癌免疫疗法开发的器官型模型的兴趣日益浓厚。这项研究回顾了片上癌症和片上免疫器官系统的最新进展，并着重介绍了它们在药物开发方面的潜力。