Synthesis ( IF 2.2 ) Pub Date : 2019-02-19 , DOI: 10.1055/s-0037-1610693 Dian Wang 1 , Xue Wang 1 , Xuange Zhang 1 , Zhiwei Miao 1, 2
|
Dedicated in celebration of the 100th anniversary of Nankai University
Abstract
The [4+3] annulation reaction of crotonate-derived sulfur ylides with benzylidenepyrazolones using K2CO3 as the base is reported. The ready availability of starting materials and the simple cyclization procedure make this approach suitable for the preparation of a diverse array of 4,7-dihydro-1H-oxepino[2,3-c]pyrazoles in good to excellent yields.
The [4+3] annulation reaction of crotonate-derived sulfur ylides with benzylidenepyrazolones using K2CO3 as the base is reported. The ready availability of starting materials and the simple cyclization procedure make this approach suitable for the preparation of a diverse array of 4,7-dihydro-1H-oxepino[2,3-c]pyrazoles in good to excellent yields.
中文翻译：
碳酸钾促进[4 + 3]巴豆酸酯衍生的硫叶立德与苯并亚苄基吡唑酮的高效合成，合成碳酸4,7-二氢-1H-氧杂环庚烷[2,3-c]吡唑
专用于100的庆典日南开大学周年
抽象的
报道了以K 2 CO 3为碱的巴豆酸衍生的硫酰化物与亚苄基吡唑并酮的[4 + 3]环化反应。原料的容易获得和简单的环化程序使该方法适用于以良好或优异的收率制备各种4,7-二氢-1 H-氧代庚并[2,3- c ]吡唑。
报道了以K 2 CO 3为碱的巴豆酸衍生的硫酰化物与亚苄基吡唑并酮的[4 + 3]环化反应。原料的容易获得和简单的环化程序使该方法适用于以良好或优异的收率制备各种4,7-二氢-1 H-氧代庚并[2,3- c ]吡唑。
京公网安备 11010802027423号