Scientific Reports ( IF 3.8 ) Pub Date : 2019-02-20 , DOI: 10.1038/s41598-019-38751-z H Fukuyama 1 , H Yagiri 2 , T Araki 1 , H Iwami 1 , Y Yoshida 1 , H Ishikawa 1 , N Kimura 1 , K Kakusho 2 , T Okadome 2 , F Gomi 1
We aimed to investigate the possible causes of metamorphopsia for rhegmatogenous retinal detachment (RRD) based on findings of enface optical coherence tomography (OCT). The study was a retrospective, consecutive case series of 33 eyes with macula-off RRD. Metamorphopsia was measured by M-CHARTS and enface OCT images covering a macular area of 6 × 6 mm square obtained at 1, 3, and 6 months postoperatively. Within the outer retinal slabs of enface OCT, multiple lines that looked like folds were delineated in all eyes at month 1, and we succeeded in extracting images of folds by subtracting retinal vessels. We calculated their density by an image-processing technique. The mean M-CHARTS scores were 0.62 ± 0.47 at month 1 and 0.30 ± 0.29 at month 6 (P < 0.001). The fold density was 8.3 ± 4.2 at month 1 and 6.1 ± 3.1 at month 6 (P = 0.0044). The M-CHARTS scores at 6 months were significantly associated with the fold density at 1 month (r = 0.515, P = 0.002). In conclusion, enface OCT visualized the outer retinal folds in eyes that had undergone successful RRD surgery, and a larger number of folds was related to the remaining metamorphopsia.
中文翻译:
玻璃体切除术治疗流源性视网膜脱离后表面光学相干断层扫描对外部视网膜褶皱进行定量评估。
我们旨在根据面相干相干断层扫描(OCT)的发现,调查变应性视网膜源性视网膜脱离(RRD)的可能原因。这项研究是一项回顾性连续病例,包括33眼黄斑剥落的RRD。通过M-CHARTS测量变态,并在术后1、3和6个月获得覆盖6×6mm见方的黄斑区域的OCT图像。在OCT眼的外部视网膜平板中,在第1个月在所有眼睛中划出了看起来像褶皱的多条线,并且我们通过减去视网膜血管成功地提取了褶皱的图像。我们通过图像处理技术计算了它们的密度。第1个月的M-CHARTS平均得分为0.62±0.47,第6个月的平均M-CHARTS得分为0.30±0.29(P <0.001)。第1个月的褶皱密度为8.3±4.2,第6个月的褶皱密度为6.1±3.1(P = 0.0044)。6个月时的M-CHARTS评分与1个月时的倍数密度显着相关(r = 0.515,P = 0.002)。总之,enface OCT可以使成功进行RRD手术的眼睛的视网膜外部褶皱可视化,并且更多的褶皱与剩余的变态有关。