Gadolinium-associated fibrotic plaques were first described by Cowper et al.¹ The term nephrogenic systemic fibrosis (NSF) was introduced later to emphasize the potential for systemic involvement. Cutaneous sclerotic bodies (ossification with trapped elastic fibers) were described as a characteristic finding in patients with gadolinium exposure and systemic fibrosis.^2- 4 In 2015, Gathings et al⁵ introduced the term gadolinium-associated plaques (GAP) to highlight the unique clinical presentation of small discrete plaques in the absence of systemic involvement or renal disease. The 2 patients they describe lacked the more common clinical findings of NSF and only 1 had renal disease. However, GAP is not universally recognized as an independent diagnostic entity. We describe the use of laser-assisted mass spectrometry to confirm deposition of gadolinium in sclerotic bodies of GAP.

per相关的纤维化斑块首先由考珀等人描述。¹肾源性系统性纤维化（NSF）一词后来被引入以强调全身性感染的潜力。皮肤硬化体（被捕获的弹性纤维骨化）被描述为exposure暴露和全身纤维化患者的特征性发现。^{2 - 4}在2015年，Gathings等人⁵引入了术语g相关斑块（GAP），以强调在没有全身性受累或肾脏疾病的情况下小的离散斑块的独特临床表现。他们描述的2例患者缺乏NSF更为常见的临床发现，只有1例患有肾脏疾病。但是，GAP未被普遍认为是独立的诊断实体。我们描述了使用激光辅助质谱法来确认g在GAP硬化体中的沉积。