This study evaluates for the first time organophosphorus flame retardant (OPFR) occurrence in the Alboran Sea delphinids (Spain). OPFRs were detected in all the individuals with concentration levels up to 24.7 µg/g lw. Twelve out of sixteen tested analytes were detected, being TBOEP which presented the highest detection frequency, and IDPP which presented the highest levels of concentration. OPFR distribution in different tissues (blubber, brain, kidney, muscle and liver) was evaluated. The pattern distribution showed the highest contribution for blubber (mean value of 68%) and the lowest contribution for liver (mean value of 2%). Seven OPFRs were detected in brain samples showing their capacity to surpass the blood-brain barrier and reach the brain. Moreover, high affinity for the brain tissue was observed. This is extremely important due to the neurotoxic effects of several compounds such as TCEP and TNBP. OPFR levels were compared with previously published PBDE concentrations, and no significant differences were observed. Taking into account the lower use and lower bioaccumulation and biomagnification capacities of OPFRs, this could indicate an additional OPFR source of pollution in addition to their use as FRs.

中文翻译：

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首次测定来自南欧水域的海豚中高含量的有机磷阻燃剂和增塑剂。

这项研究首次评估了有机磷阻燃剂（OPFR）在Alboran Sea delphinids（西班牙）中的发生。在所有个体中检测到的OPFR浓度最高为24.7 µg / g lw。在十六种测试分析物中，有十二种被检测到，其中TBOEP代表最高的检测频率，IDPP代表最高的浓度。评估了不同组织（脂肪，大脑，肾脏，肌肉和肝脏）中的OPFR分布。模式分布显示，对润滑脂的贡献最大（平均值为68％），对肝脏的贡献最小（平均值为2％）。在大脑样本中检测到7种OPFR，表明它们具有超过血脑屏障并到达大脑的能力。此外，观察到对脑组织的高亲和力。由于多种化合物（如TCEP和TNBP）的神经毒性作用，这一点极为重要。将OPFR水平与先前公布的PBDE浓度进行了比较，未观察到显着差异。考虑到OPFRs的使用量较低，生物蓄积和生物放大能力较低，这可能表明除了将其用作FRs外，OPFR还会增加污染源。