3D multiporous Co, N co-doped MoO₂/MoC (3D Co,N-MoO₂/MoC) nanorods hybrids were successfully synthesized via carburizing core-shell ZIF-67-cladded MoO₃ nanorods precursor at high temperature. As-fabricated Co,N-MoO₂/MoC nanorods coated glassy carbon electrodes (GCE) was demonstrated to possess superior electrocatalytic activity for the electro-oxidation of acetaminophen (AC) and 4-aminophenol (4-AP). Such excellent electrochemical performance was largely attributed to the synergistic effect of the unique multiporous structure, the optimal component and abundant active sites of the nanorods. The corresponding electrode reaction mechanisms were studied in detail in this article. Under optimal conditions, the linear detection ranges were 0.05–200.0 μmol/L for AC and 0.05–140.0 μmol/L for 4-AP, respectively, with the low detection limits of 0.013 μmol/L and 0.012 μmol/L. Furthermore, the 3D Co,N-MoO₂/MoC/GCE revealed excellent sensitivity, good reproducibility, stability and anti-interference ability. The developed electrode was evaluated towards the detecting AC and 4-AP in biological fluids, environment water and pharmaceutical formulations with satisfactory recovery, which had a broad application prospect.

通过在高温下渗碳核-壳ZIF-67包覆的MoO ₃纳米棒前驱体成功合成了3D多孔Co，N共掺杂的MoO ₂ / MoC（3D Co，N-MoO ₂ / MoC）纳米棒杂化物。预制的Co，N-MoO ₂已证明/ MoC纳米棒涂覆的玻璃碳电极（GCE）具有对乙酰氨基酚（AC）和4-氨基苯酚（4-AP）电氧化的优异电催化活性。如此优异的电化学性能很大程度上归因于独特的多孔结构，纳米棒的最佳组分和丰富的活性位点的协同效应。本文详细研究了相应的电极反应机理。在最佳条件下，AC的线性检测范围为0.05–200.0μmol/ L，4-AP的线性检测范围为0.05–140.0μmol/ L，低检测限为0.013μmol/ L和0.012μmol/ L。此外，3D Co，N-MoO ₂/ MoC / GCE显示出优异的灵敏度，良好的重现性，稳定性和抗干扰能力。对开发的电极进行了评估，以检测生物流体，环境水和药物制剂中的AC和4-AP，回收率令人满意，具有广阔的应用前景。