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Biomimetic Scaffolds: 3D Molecularly Functionalized Cell‐Free Biomimetic Scaffolds for Osteochondral Regeneration (Adv. Funct. Mater. 6/2019)
Advanced Functional Materials ( IF 18.5 ) Pub Date : 2019-02-05 , DOI: 10.1002/adfm.201970036
Lan Li 1 , Jiayi Li 2 , Jiamin Guo 3 , Huikang Zhang 2 , Xin Zhang 1 , Caiyun Yin 1 , Liming Wang 2 , Yishen Zhu 1 , Qingqiang Yao 2
Affiliation  

In article number 1807356, Yishen Zhu, Qingqiang Yao, and co‐workers develop a strategy to molecularly functionalize the self‐assembling peptide hydrogel (SAPH) FEFEFKFK onto 3D‐printed polycaprolactone (PCL) scaffolds, forming a reliable and stable coating layer. The prepared SAPH‐coated PCL scaffolds provide a superior performance for the regeneration of cartilage and subchondral bone simultaneously, offering a flexible strategy for osteochondral defects caused by osteoarthritis or acute trauma.
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中文翻译:

仿生支架:用于软骨软骨再生的3D分子功能化无细胞仿生支架(Adv。Funct。Mater。6/2019)

在1807356号文章中,朱以深,姚庆强及其同事开发了一种将自组装肽水凝胶(SAPH)FEFEFKFK分子功能化到3D打印的聚己内酯(PCL)支架上的策略,从而形成可靠而稳定的涂层。制备的SAPH涂层PCL支架可同时提供出色的软骨和软骨下骨再生性能,为因骨关节炎或急性创伤引起的骨软骨缺损提供灵活的策略。
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更新日期:2019-02-05
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