We synthesized an optically active 4,4,4-trifluoro-3-{4-(4-methoxyphenyl)phenyl}butanoic acid (5^*). New chiral dopants for nematic liquid crystals were derived from (R)-(−)-5^*, and their helical twisting power (HTP) values were measured. Their HTP values were largely influenced by the linkage between the asymmetric frame and the core moiety. The chiral dopant, (R)-(+)-4,4,4-trifluoro-1-(4-hexyloxyphenyl)-3-{4-(4-methoxyphenyl)phenyl}-1-butanone ((R)-(+)-7^*) showed the largest HTP value (−21.7 μm⁻¹).

中文翻译：

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旋光的4,4,4-三氟-3- {4-（4-甲氧基苯基）苯基}丁酸的合成及其在向列型液晶手性掺杂剂中的应用

我们合成了一种旋光的4,4,4-三氟-3- {4-（4-甲氧基苯基）苯基}丁酸（5 ^*）。从（R）-（-）- 5 ^*衍生出用于向列型液晶的新手性掺杂剂，并测量了其螺旋扭曲力（HTP）值。它们的HTP值很大程度上受不对称框架和核心部分之间的联系的影响。手性掺杂剂，（R）-（+）-4,4,4-三氟-1-（4-己基氧基苯基）-3- {4-（4-甲氧基苯基）苯基} -1-丁酮（（R）-（ +）- 7 ^*）显示最大的HTP值（-21.7μm ^-1）。