The use of neopentylphosphine ligands in the palladium-catalyzed Suzuki, Sonogashira, Heck, and Hartwig–Buchwald couplings of aryl bromides and chlorides are reported. Di-tert-butylneopentylphosphine (DTBNpP) provided highly active catalysts for the coupling of aryl bromides at mild temperatures. Trineopentylphosphine, an air-stable trialkylphosphine, gave inactive catalysts at room temperature, but showed good activity in the H–B amination of aryl chlorides at elevated temperatures.

中文翻译：

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新戊基膦作为钯催化的芳基溴化物和氯化物交叉偶联的有效配体

据报道，新戊基膦配体在钯催化的Suzuki，Sonogashira，Heck和Hartwig-Buchwald芳基溴化物和氯化物偶联反应中使用。二-叔-butylneopentylphosphine（DTBNpP）对于芳基溴的在温和的温度的耦合提供高活性催化剂。脯氨酰叔丁基膦，一种空气稳定的三烷基膦，在室温下可提供惰性催化剂，但在升高的温度下芳基氯化物的H–B胺化反应中表现出良好的活性。