4-Oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid ethyl ester was obtained when TosMIC was reacted with 3-methylene-oxindole acetic acid ethyl ester. An alternative synthesis to this pyrroloquinolone was performed via a reduction of a 2,3,4-trisubstituted pyrrole obtained in turn by treatment of a vinyl sulfone with ethyl isocyanoacetate under basic conditions. A β-carboline, isomeric with the pyrroloquinolone, was synthesised utilizing a tosylimine.

中文翻译：

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4-oxo-4,5-dihydro-3 H-吡咯并[2,3 - c ]喹啉-1-羧酸乙酯及其异构体1-oxo-2,9-dihydro-1 H -β-咔啉的合成-4-羧酸乙酯

当TosMIC与3-亚甲基-氧吲哚乙酸乙酯反应时，得到4-Oxo-4，5-二氢-3 H-吡咯并[2，3 - c ]喹啉-1-羧酸乙酯。该吡咯并喹诺酮的另一种合成是通过还原2,3,4-三取代的吡咯而完成的，该吡咯并通过在碱性条件下用异氰基乙酸乙酯处理乙烯基砜而得到。利用甲苯磺胺合成了与吡咯并喹诺酮同分异构的β-咔啉。