Inactive chaparrin has been converted in seven steps and in 16% overall yield to castelanone which is known to inhibit significantly growth of the murine lymphocytic leukemia P-388 cell line. The methodology developed has been applied to the preparation of quassinoid analogs , and .

中文翻译：

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拟似系列的综合研究。查帕林将其转化为二十烷酮和类茜素类似物。

失活的查帕林经过七个步骤，以总收率的16％转化为Castelanone ，众所周知，Caselanone可以显着抑制鼠淋巴细胞性白血病P-388细胞系的生长。开发的方法已应用于拟拟南芥类似物，和。