The synthesis of pyrazino[1,2-a]indoles via a palladium-catalyzed double allylic alkylation of indole-2-hydroxamates is described. The reaction conditions are very mild and allow for a wide variety of substitutions on the indole core.

中文翻译：

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吲哚-2-异羟肟酸酯的钯催化双烯丙基烷基化：易于获得吡嗪并[1,2- a ]吲哚衍生物

描述了通过钯催化的吲哚-2-异羟肟酸酯的双烯丙基烷基化反应合成吡嗪并[1,2- a ]吲哚。反应条件非常温和，并允许在吲哚核上进行各种各样的取代。