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Determination of the absolute configuration of 1,3,5-triphenyl-4,5-dihydropyrazole enantiomers by a combination of VCD, ECD measurements, and theoretical calculations
Tetrahedron: Asymmetry Pub Date : 31 May 2011 , DOI: 10.1016/j.tetasy.2011.06.003
Nicolas Vanthuyne , Christian Roussel , Jean-Valère Naubron , Nadine Jagerovic , Paula Morales Lázaro , Ibon Alkorta , José Elguero

The enantiomers of 1,3,5-triphenyl-4,5-dihydropyrazole (an intense blue fluorescent compound) have been separated for the first time and their absolute configuration was established by a combination of VCD and ECD measurements and theoretical calculations. The enantiomers of 1,3,5-triphenyl-4,5-dihydropyrazole which are highly fluorescent both in solution (CH2Cl2) and in the solid state may find application in the very active field of enantioselective fluorosensors.

中文翻译:

结合VCD,ECD测量和理论计算确定1,3,5-三苯基-4,5-二氢吡唑对映体的绝对构型

1,3,5-三苯基-4,5-二氢吡唑(一种强蓝色荧光化合物)的对映体是首次分离,并且通过VCD和ECD测量及理论计算的组合确定了它们的绝对构型。1,3,5-三苯基-4,5-二氢吡唑的对映异构体在溶液(CH 2 Cl 2)和固态下均具有高荧光性,可用于对映选择性氟传感器的非常活跃的领域。
更新日期:2017-01-31
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