Diethy (N-methoxy-N-methylcarbamoylmethyl)phosphonate (1) is easily prepared by heating 2-chloro-N-methoxy-N-methylethanamide and triethylphosphite. Reagent 1 is useful for converting aldehydes and ketones into compounds containing an α,β-unsaturated N-methoxy-N-methylamide group with high E selectivity.

中文翻译：

---

（N-甲氧基-N-甲基氨基甲酰基甲基）膦酸二乙酯-一种有用的Emmons-Horner Wittig试剂

通过加热2-氯-N-甲氧基-N-甲基乙酰胺和亚磷酸三乙酯，可以容易地制备二乙氧基（N-甲氧基-N-甲基氨基甲酰基甲基）膦酸酯（1）。试剂1可用于以高E选择性将醛和酮转化为含有α，β-不饱和N-甲氧基-N-甲基酰胺基的化合物。