Root organogenesis after tissue damage is a type of plant regeneration known as de novo root regeneration (DNRR). The DNRR process is widely exploited in agricultural technologies, such as cuttings for vegetative propagation. This review summarizes recent advances in our understanding of the cellular and molecular framework of DNRR, mainly focusing on rooting from Arabidopsis thaliana leaf explants. The framework comprises three successive phases, that is, early signaling, auxin accumulation, and cell fate transition, and involves two types of cells with different functions: the converter cell that converts the early signals as the input into auxin flux as the output; and the regeneration-competent cell that undergoes fate transition guided by auxin.

组织损伤后根器官是一类已知为植物再生的从头根再生（DNRR）。DNRR过程已广泛用于农业技术中，例如无性繁殖的插条。这篇综述总结了我们对DNRR的细胞和分子框架的理解的最新进展，主要侧重于拟南芥叶片外植体的生根。该框架包括三个连续的阶段，即早期信号传递，植物生长素蓄积和细胞命运转变，并涉及两种具有不同功能的细胞：转化细胞，将早期信号作为输入转化为生长素通量作为输出；以及在生长素的指导下经历命运转变的具有再生能力的细胞。