当前位置: X-MOL 学术Tetrahedron › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Synthesis of compounds related to vinca alkaloids : Stereoselective synthesis of (±) homoeburnamine
Tetrahedron ( IF 2.1 ) Pub Date : 1978 , DOI: 10.1016/0040-4020(78)88023-5
A. Buzas , C. Retourne , J.P. Jacquet , G. Lavielle

Base catalysed addition of acrolein to 1-ethyl-2,3,4,6,7,12-hexahydroindolo[2,3a] quinolizine (perch-lorate) 5b gives a pentacyclic alcohol 6b, which can be reduced in excellent yield to (±) homoeburnamine 7, a convenient precursor of (±) homoeburnamenine 9 and (±) homoeburnamonine 11.

中文翻译:

长春花生物碱相关化合物的合成:(±)高纯胺的立体选择性合成

碱催化将丙烯醛加到1-乙基-2,3,4,6,7,12-六氢吲哚并[2,3a]奎宁嗪(高氯酸盐)5b中可得到五环醇6b,可将其优良的产率降低为( ±)homoeburnamine 7,(±)homeburnamenine 9和(±)homoeburnamonine 11的便利前体。
更新日期:2017-01-31
down
wechat
bug