Two simple and efficient methods for the conversion of the naturally occurring alkaloid, camptothecin to mappicine ketone, an antiviral lead compound, have been described. The first method involved the treatment of camptothecin with borontrifluoride etherate and the second method utilised the microwave irradiation of the alkaloid.

中文翻译：

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将喜树碱转化为抗病毒先导化合物吗啡酮的两种有效方法

已经描述了两种简单有效的方法将天然生物碱喜树碱转化为抗病毒的先导化合物吗啡酮。第一种方法涉及用三氟化硼醚化物处理喜树碱，第二种方法利用生物碱的微波辐射。