The first total synthesis of (3S,6R)-3,6-dihydroxy-10-methylundecanoic acid was accomplished from commercially available 1-bromo-3-methylbutane in 11 steps and 25.8% overall yield. The key steps were asymmetric allylic alkylations via allyldiisopinocampheylborane and hydroboration–oxidation.

中文翻译：

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第一次全合成（-）-（3 S，6 R）-3,6-二羟基-10-甲基十一酸

（3 S，6 R）-3,6-二羟基-10-甲基十一烷酸的第一个总合成是从商业上可获得的1-溴-3-甲基丁烷分11步完成的，总收率为25.8％。关键步骤是通过烯丙基二异opinocampheylborane的不对称烯丙基烷基化和硼氢化-氧化。