4-Methoxytrityl (Mmt)-mercapto acids were obtained either by the reaction of mercapto acids with Mmt-chloride or by the reaction of halo acids with Mmt-thiol. The derivatives obtained were used in the solid-phase synthesis of small libraries of mercaptoacylamino acids and mercaptoacyl peptides. The removal of the Mmt-group was performed by treatment with trifluoroacetic acid (TFA) in dichloromethane (DCM) using triethylsilane (TES) as scavenger.

中文翻译：

---

S -4-甲氧基三苯甲基巯基酸的合成与应用

通过巯基酸与Mmt-氯化物的反应或通过卤代酸与Mmt-硫醇的反应，获得4-甲氧基三苯甲基（Mmt）-巯基酸。获得的衍生物用于巯基酰基氨基酸和巯基酰基肽的小文库的固相合成。通过使用三乙基硅烷（TES）作为清除剂，在二氯甲烷（DCM）中用三氟乙酸（TFA）处理，可以去除Mmt基团。