Red Blood Cells for Drug Delivery,Small Methods

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Red Blood Cells for Drug Delivery
Small Methods ( IF 10.7 ) Pub Date : 2017-11-14 , DOI: 10.1002/smtd.201700270
Junjie Yan ₁ , Jicheng Yu ₁ , Chao Wang ₁ , Zhen Gu _{1,

2}

Affiliation

Red blood cells (RBCs), or erythrocytes, have been promising endogenous candidates for drug delivery for more than four decades. Armed with a better understanding of the diverse mechanisms and paths for drug delivery, researchers have achieved great progress in manufacturing RBC‐based carriers, from both the scientific and clinical viewpoints. Here, the loading methods and loading therapeutics by RBC carriers are surveyed, and recent advances in the design of stimuli‐triggered RBC carriers highlighted. Key developing trends and challenges, are also discussed, and an outlook is presented.

中文翻译：

用于药物输送的红细胞

红细胞（RBC）或红细胞在过去的四十年中一直是有前途的内源性候选药物。有了对药物输送的多种机制和途径的更好的了解，研究人员从科学和临床的观点来看，在制造基于RBC的载体方面都取得了巨大的进步。在此，对RBC载体的加载方法和加载疗法进行了调查，并重点介绍了刺激触发的RBC载体设计的最新进展。还讨论了主要的发展趋势和挑战，并提出了展望。

更新日期：2017-11-14

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