Monosubstituted tricyclo[2.1.0.0^2,5]pentan-3-one derivatives have been synthesised and subjected to hydride reduction. Quite unexpectedly and in contrast to earlier observations in related systems, anti-selectivity has been encountered in these substrates. Computational studies employing various models reproduce the observed facial preference and indicate that the causative factor for the anti-preference could be the polarization of the C1C5 strained σ bond.

中文翻译：

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三环[2.1.0.0 ^2,5 ] pentan-3-one系统：研究亲核加成中的π面选择性的新探针

已经合成了单取代的三环[2.1.0.0 ^2,5 ]戊丹-3-酮衍生物并将其还原为氢化物。出乎意料的是，与相关系统中的早期观察结果相反，在这些底物中遇到了抗选择性。使用各种模型进行的计算研究重现了观察到的面部偏爱，并表明反偏爱的原因可能是C1C5应变σ键的极化。