当前位置: X-MOL 学术Chem. Eur. J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Palladium‐Catalyzed Arylation of Unactivated γ‐Methylene C(sp3)?H and δ‐C?H Bonds with an Oxazoline‐Carboxylate Auxiliary
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2015-10-07 , DOI: 10.1002/chem.201502621
Peng-Xiang Ling , Sheng-Long Fang , Xue-Song Yin , Kai Chen , Bo-Zheng Sun , Bing-Feng Shi

A palladium‐catalyzed arylation of unactivated γmethylene C(sp3)H and remote δ‐CH bonds by using an oxazoline‐carboxylate directing group has been developed. Arylation occurs with a broad substrate scope and high tolerance of functional groups (i.e., halogen, nitro, cyano, ether, trifluoromethyl, amine, and ester). The oxazoline‐type auxiliary can be removed under acidic conditions.

中文翻译:

钯催化未活化的γ-亚甲基C(sp3)的芳基化作用H和δ-C 含恶唑啉-羧酸盐助剂的H键

未活化的γ的钯-催化的芳基化-亚甲基C(SP 3 H和远程δ-C H键通过使用恶唑啉甲酸甲酯定向基团已被开发。在广泛的底物范围和对官能团(即卤素,硝基,氰基,醚,三氟甲基,胺和酯)的高耐受性下发生丙烯酸化。可以在酸性条件下除去恶唑啉型助剂。
更新日期:2015-10-07
down
wechat
bug