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Germacrane‐Type Sesquiterpenes from Curcuma wenyujin
Helvetica Chimica Acta ( IF 1.5 ) Pub Date : 2009-08-20 , DOI: 10.1002/hlca.200900059
Yan Lou , Feng Zhao , Zhaohua Wu , Kai‐Feng Peng , Xing‐Chuan Wei , Li‐Xia Chen , Feng Qiu

Two new germacrane‐type sesquiterpene lactones, curdionolides A and B (1 and 2, resp.), and a novel germacrane‐type sesquiterpene lactam, curdionolide C (3), were isolated from Curcuma wenyujin. Y. H. Chen et C. Ling together with five known germacrane‐type sesquiterpenes, 48. The structures of the new compounds were elucidated by spectroscopic methods. The inhibitory effects of compounds 18 on nitric oxide (NO) production in lipopolysaccharide‐activated macrophages were evaluated.

中文翻译:

姜黄中的Germacrane型倍半萜烯

从姜黄姜中分离出两个新的麦加兰型倍半萜内酯,姜黄素内酯A和B(分别为12),以及一个新的麦加兰型倍半萜内酰胺,姜黄素内酯C(3Y. H. Chen等C.泠与5种已知吉马烷型倍半萜烯,一起4 - 8。通过光谱方法阐明了新化合物的结构。评估了化合物18对脂多糖激活的巨噬细胞中一氧化氮(NO)产生的抑制作用。
更新日期:2009-08-20
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