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An Efficient and Economical Method for the Preparation of Fmoc‐Argω,ω′(Boc)2‐OH
Chinese Journal of Chemistry ( IF 5.5 ) Pub Date : 2010-09-06 , DOI: 10.1002/cjoc.201090257
Ruixin Zhu , Ming Xie , Fei Wang , Qi Liu , Tingguo Kang

The arginine derivative Fmoc‐Argω,ω(Boc)2‐OH has been prepared in perfect yield starting from Fmoc‐Orn·HCl and N,N′‐di‐Boc‐N′′‐triflyguanidine with the presence of diisopropylethylamine (DIEA). This work provides an efficient and economical method for the preparation of this compound.

中文翻译:

一种高效经济的制备Fmoc-Argω,ω'(Boc)2-OH的方法

精氨酸衍生物的Fmoc精氨酸ωω '(BOC)2 -OH已经完善收率由Fmoc-ORN·HCl和开始制备ÑN' -二-制备Boc- N'' -triflyguanidine与二异丙基乙胺的存在下( DIEA)。这项工作为制备该化合物提供了一种有效而经济的方法。
更新日期:2010-09-06
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