Regulation of AMPA receptors mediates homeostatic scaling. In this issue of Neuron, Wang et al. (2017) identify a new role of secreted semaphorin 3F and elucidate how it triggers synaptic downscaling of AMPA receptors through regulation of the binding of Sema3F holoreceptor complex to AMPA receptors.

中文翻译：

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Semaphorin对AMPA受体进行稳态缩放。

AMPA受体的调节介导稳态缩放。在Neuron的这一期中，Wang等人。（2017）确定了分泌的信号量3F的新作用，并阐明了它如何通过调节Sema3F全息感受器复合物与AMPA受体的结合来触发AMPA受体的突触缩小。