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Cryopreservation: Hydrogel Encapsulation Facilitates Rapid‐Cooling Cryopreservation of Stem Cell‐Laden Core–Shell Microcapsules as Cell–Biomaterial Constructs (Adv. Healthcare Mater. 23/2017)
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2017-12-06 , DOI: 10.1002/adhm.201770117
Gang Zhao 1 , Xiaoli Liu 1 , Kaixuan Zhu 1 , Xiaoming He 2
Affiliation  

Gang Zhao and co‐workers develop a rapid cryopreservation method for large‐volume stem cell hydrogel constructs in article number 1700988. Stem cells encapsulated in core‐shell microcapsules retain their multipotential differentiation capability, and survive well when subjected to visible ice formation during cooling and subsequent ice formation during re‐warming, a so‐called devitrification process that is considered to be lethal for cells in long‐term cryopreservation.
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中文翻译:

冷冻保存:水凝胶封装有助于将干细胞载有核-壳微胶囊作为细胞-生物材料构建体进行快速冷却冷冻保存(Adv。Healthcare Mater。23/2017)

赵刚及其同事在文章编号1700988中开发了一种用于大容量干细胞水凝胶构建体的快速冷冻保存方法。包裹在核壳微胶囊中的干细胞保留了其多能分化能力,并且在冷却和冷却过程中受到可见的冰形成时可以很好地存活。随后在重新加温过程中形成冰块,这是所谓的失透过程,在长期低温保存中,这种过程被认为对细胞具有致命性。
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更新日期:2017-12-06
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