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Direct One-Pot Synthesis of Luotonin F and Analogues via Rational Logical Design
Organic Letters ( IF 4.9 ) Pub Date : 2012-12-28 00:00:00 , DOI: 10.1021/ol303331g
Yan-ping Zhu 1 , Zhuan Fei 1 , Mei-cai Liu 1 , Feng-cheng Jia 1 , An-xin Wu 1
Affiliation  

An efficient one-pot synthetic protocol has been proposed for the synthesis of luntonin F from easily available starting materials. Through a rational logical design, multifundamental reactions (iodination, Kornblum oxidation, and annulation) were assembled in one-pot. The developed approach can efficiently synthesize luntonin F and a diversity of analogues.

中文翻译:

理性逻辑设计直接一锅法合成褪黑素F及其类似物

已经提出了一种有效的一锅法合成方案,用于从容易获得的起始原料合成luntoninF。通过合理的逻辑设计,在一锅中组装了多种基本反应(碘化,科恩布鲁姆氧化和环化反应)。所开发的方法可以有效地合成luntonin F和多种类似物。
更新日期:2012-12-28
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