A novel copper-catalyzed cascade cyclization of easily prepared 2-propynolphenols with disubstituted phosphine oxides has been developed to give 4-phosphorylated 2H-chromenes in moderate to excellent yields. This cascade process involves multiple bond-forming events including C–O and C–P bonds. Moreover, both tertiary and secondary propargylic alcohols with diverse functional groups showed excellent compatibilities under ligand- and additive-free conditions.

中文翻译：

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铜催化的2-丙酚酚的级联环化：获得4-磷酸化的2H-Chromenes。

已经开发了新颖的铜催化的易于制备的2-丙炔酚与双取代的氧化膦的级联环化反应，以中等至极好的收率得到了4-磷酸化的2 H-色烯。这种级联过程涉及多个键形成事件，包括C–O和C–P键。此外，具有各种官能团的叔炔丙醇和仲炔丙醇在无配体和无添加剂的条件下均显示出优异的相容性。