A novel method is developed for the oxidation of thiols to the corresponding disulfides using 20mol% haloacid (HBr or HI) in combination with dimethyl sulfoxide. A tentative mechanism is proposed for the oxidation. In addition to the advantages of cost-effectiveness, simple processes, and broad functional group tolerance, the exclusive formation of disulfides is the principle reward of this methodology while compared to known methods that further oxidize disulfides to S-oxides and other byproducts.

中文翻译：

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卤酸/二甲亚砜催化硫醇氧化合成对称二硫化物

开发了一种新方法，可结合使用20摩尔％的卤酸（HBr或HI）和二甲基亚砜将硫醇氧化为相应的二硫化物。提出了一种初步的氧化机理。除了具有成本效益，简单的方法和广泛的官能团耐受性的优点外，与已知的方法进一步将二硫化物进一步氧化为S-氧化物和其他副产物相比，仅形成二硫化物是该方法的主要优点。