A novel vinyl ether-type RAFT agent, benzyl 2-(vinyloxy)ethyl carbonotrithioate (BVCT) was synthesized for various block copolymers via the combination of living cationic polymerization of vinyl ethers and reversible addition−fragmentation chain transfer (RAFT) polymerization. The novel BVCT–trifluoroacetic acid adduct play an important role to produce well-defined block copolymers, which is both as a cationogen under EtAlCl₂ initiation system in the presence of ethyl acetate for living cationic polymerization and a RAFT agent for blocks by RAFT polymerization. The resulting polymer, poly(vinyl ether)s, by living cationic polymerization had a high number average α-end functionality (≥0.9) as determined by both ¹H NMR and MALDI-TOF-MS spectrometry. In addition, this poly(vinyl ether)s worked well as a macromolecular chain transfer agent for RAFT polymerization. The RAFT polymerization of radically polymerizable monomers was conducted in toluene using 2,2′-azobis(isobutyronitrile) at 70 °C. For example, a double thermoresponsive block copolymer (MOVE₆₁-b-NIPAM₁₅₀) consisting of 2-methoxyethyl vinyl ether (MOVE) and N-isopropylacrylamide (NIPAM) was prepared via the combination of living cationic polymerization and RAFT polymerization. The block copolymer reversibly formed and deformed micellar assemblies above the phase separation temperature (T_ps) of poly(NIPAM) block in water. This BVCT is not only functioned as an initiator, but also acted as a monomer. When BVCT was copolymerized with MOVE by living cationic polymerization, followed by graft copolymerization with NIPAM via RAFT polymerization, well-defined graft copolymers (MOVE_n-co-BVCT_m)-g-NIPAM_x (n = 62–73, m = 1–9, x = 19–214) were successfully obtained. However, no micelle formed in water above T_ps of poly(NIPAM) graft chain unlike the case of block copolymers.

通过乙烯基醚的活性阳离子聚合与可逆加成-断裂链转移（RAFT）聚合相结合，合成了一种新型的乙烯基醚型RAFT剂2-三乙烯基苄基（CV）的碳三硫代酸酯（BVCT）。新型的BVCT-三氟乙酸加合物在生产定义明确的嵌段共聚物中起着重要作用，该嵌段共聚物既在EtAlCl ₂引发体系下，在乙酸乙酯存在下作为阳离子阳离子用于活性阳离子聚合，又作为RAFT试剂用于RAFT聚合用于嵌段。将得到的聚合物，聚（乙烯基醚）类，通过活性阳离子聚合具有如通过确定高的数均α-端功能（≥0.9）¹1 H NMR和MALDI-TOF-MS光谱。另外，该聚乙烯醚作为用于RAFT聚合的大分子链转移剂很好地起作用。自由基可聚合单体的RAFT聚合是在70°C下使用2,2'-偶氮二（异丁腈）在甲苯中进行的。例如，通过活性阳离子聚合和RAFT聚合的组合，制备了由2-甲氧基乙基乙烯基醚（MOVE）和N-异丙基丙烯酰胺（NIPAM）组成的双热响应性嵌段共聚物（MOVE ₆₁ - b- NIPAM ₁₅₀）。高于相分离温度（T _ps）的嵌段共聚物可逆地形成和变形的胶束组件。（NIPAM）嵌段在水中）。该BVCT不仅起引发剂的作用，而且还起单体的作用。当BVCT通过活性阳离子聚合与MOVE共聚，然后通过RAFT聚合与NIPAM接枝共聚时，定义明确的接枝共聚物（MOVE _n - co -BVCT _m）-g -NIPAM _x（n  = 62-73，m  = 1 –9，x  = 19–214）已成功获得。然而，与嵌段共聚物的情况不同，在聚（NIPAM）接枝链的T _ps以上的水中没有形成胶束。