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Lignans from the roots of Kadsura coccinea and their inhibitory activities on LPS-induced NO production
Phytochemistry Letters ( IF 1.3 ) Pub Date : 2014-06-23 , DOI: 10.1016/j.phytol.2014.06.005
Lingzhi Fang , Chunfeng Xie , Hao Wang , Da-Qing Jin , Jing Xu , Yuanqiang Guo , Yonggang Ma

Three new lignans 14-O-demethyl polysperlignan D (1), kadsurindutin E (16), coccilignan A (17), and fifteen known lignan compounds (215 and 18) were isolated from the roots of Kadsura coccinea. Their structures were elucidated on the basis of detailed spectroscopic analyses (IR, ESIMS, HR-ESIMS, 1D and 2D NMR, and CD). The NO production inhibitory activities of these isolated lignans were also evaluated.



中文翻译:

来自Kadsura coccinea根的木质素及其对LPS诱导的NO产生的抑制活性

三个新的木脂素-14- ö -demethyl polysperlignan d(1),kadsurindutin E(16),coccilignan A(17),和15木酚素化合物已知的(2 - 1518)从根分离南五味子红花。根据详细的光谱分析(IR,ESIMS,HR-ESIMS,1D和2D NMR和CD)阐明了它们的结构。还评估了这些分离的木脂素的NO产生抑制活性。

更新日期:2014-06-23
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