A convergent synthesis applicable to the preparation of oxidized prenylchalcones is reported that relies on key Claisen–Schmidt, Mitsunobu, and vinyl/benzyl Stille coupling operations. The synthetic strategy was applied towards the preparation of the natural products morachalcone A and isogemichalcones B & C, allowing their preparation in less than 10 steps and 6–8% overall yield.

中文翻译：

---

天然存在的芳香化酶抑制剂的合成制剂，morachalcone A，isogemichalcone B和isogemichalcone C

据报道，适用于制备氧化苯甲腈的聚合合成依赖关键的克莱森-施密特，光信和乙烯基/苄基斯蒂勒偶联操作。合成策略应用于朝向天然产物的制备morachalcone A和isogemichalcones B＆C，允许它们在小于10个步骤和6-8％的总收率制备。