Tetrahedron Letters ( IF 1.5 ) Pub Date : 2014-11-22 , DOI: 10.1016/j.tetlet.2014.11.077 Jun Chang , Zhi-Bo Chu , Jiao Song , Lin Jin , Xun Sun
Two new isoquinoline alkaloids, decumbensine (1) and decumbendine (2), together with nine known compounds including tetrahydropalmatine (3), bicuculline (4), allocryptopine (5), bulbocapine (6), protopine (7), kikemanine (8), decumbenine B (9), decumbenine C (10), and muramine (11) were isolated from the seedling of Corydalis decumbens (Thunb.) Pers. (Papaveraceae). Their structures were decisively elucidated by spectroscopic analysis including 1D and 2D NMR techniques. Furthermore, the biogenetic pathways of two new compounds were proposed, which would provide valuable information for further understanding of the isoquinoline alkaloids of C. decumbens.
中文翻译:
延胡索子幼苗中的两种新型异喹啉生物碱
两个新的异喹啉生物碱,decumbensine(1)和decumbendine(2),与九个已知化合物,包括延胡索(一起3),荷包牡丹碱(4),别隐品碱(5),bulbocapine(6),普罗托(7),kikemanine(8)从延胡索的幼苗中分离到了苯地宁B(9),苯地宁C(10)和尿素(11)。(大喇叭)Pers。(罂粟科)。通过包括1D和2D NMR技术在内的光谱分析可以明确地阐明它们的结构。此外,提出了两种新化合物的生物遗传途径,这将为进一步了解角皮梭菌的异喹啉生物碱提供有价值的信息。