The fluorine-containing organic compounds are becoming privileged in medicinal chemistry. Described herein is an efficient and environmental friendly method for the synthesis of the gem-difluoromethylene azo compounds without any additives, and the hydrogen bond between water and fluorinated enol silyl ether slightly promote the reaction.

中文翻译：

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由Arenediazonium盐和氟化烯醇甲硅烷基醚“全水”合成宝石-二氟亚甲基偶氮化合物

含氟有机化合物在药物化学中正变得尤为重要。本文描述了一种不加任何添加剂的合成宝石-二氟亚甲基偶氮化合物的有效且环境友好的方法，并且水与氟化烯醇甲硅烷基醚之间的氢键略微促进了反应。